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Dragon Quest X will reportedly put more of a focus on story, despite being an MMORPG.  Parties will have a designated “story leader” whom story events will consider the main character, with the rest of the party simply supporting in battle.  DQX‘s five continents will also feature various regional plots: an elven land facing destruction for lack of an important ceremony, a kingdom blighted by a mysterious plague, another country where children are suddenly going missing, and so on.

Additionally, it was confirmed that the game will see quests added post-release, and Square Enix is currently developing quests for each job, race, and continent.

Source: Andriasang